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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM2
All Species:
43.94
Human Site:
T805
Identified Species:
64.44
UniProt:
P49736
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49736
NP_004517.2
904
101896
T805
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Chimpanzee
Pan troglodytes
XP_001136482
895
100908
T796
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Rhesus Macaque
Macaca mulatta
XP_001099580
870
97929
I771
V
R
H
M
E
S
M
I
R
M
F
S
V
M
R
Dog
Lupus familis
XP_541736
1001
113024
T902
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Cat
Felis silvestris
Mouse
Mus musculus
P97310
904
102059
T805
M
M
E
S
F
I
D
T
Q
K
F
S
V
M
R
Rat
Rattus norvegicus
NP_001101343
905
102125
T806
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518428
911
102482
T812
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Chicken
Gallus gallus
NP_001006139
888
100332
T789
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Frog
Xenopus laevis
P55861
886
100243
T787
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Zebra Danio
Brachydanio rerio
NP_775364
880
98286
T781
M
L
E
S
F
I
D
T
Q
K
F
S
V
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
A782
M
L
E
S
F
I
E
A
Q
K
F
S
V
M
K
Honey Bee
Apis mellifera
XP_395109
1005
114136
S904
F
V
D
T
Q
K
Y
S
V
M
K
S
M
R
Q
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
T678
S
T
I
E
A
A
A
T
G
N
L
A
G
V
E
Sea Urchin
Strong. purpuratus
XP_001177558
884
100012
T785
M
L
E
S
F
I
D
T
Q
K
Y
S
I
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
P687
H
G
S
S
G
N
D
P
M
D
V
D
V
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29469
868
98761
K785
L
H
Q
M
D
M
D
K
V
S
R
V
Y
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.8
87.4
N.A.
95.5
96
N.A.
93.1
88.2
86.7
80.1
N.A.
63.9
58.4
26.7
73.4
Protein Similarity:
100
99
96.1
89.1
N.A.
97.7
98.3
N.A.
95.7
93.8
93
87.6
N.A.
79.3
73.5
43.2
86.5
P-Site Identity:
100
100
33.3
100
N.A.
93.3
100
N.A.
100
100
100
100
N.A.
80
6.6
6.6
86.6
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
46.6
20
100
Percent
Protein Identity:
N.A.
30.3
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
48.8
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
7
7
0
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
75
0
0
7
0
7
0
0
7
% D
% Glu:
0
0
69
7
7
0
7
0
0
0
0
0
0
0
7
% E
% Phe:
7
0
0
0
69
0
0
0
0
0
69
0
0
0
0
% F
% Gly:
0
7
0
0
7
0
0
0
7
0
0
0
7
7
0
% G
% His:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
69
0
7
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
7
0
7
0
69
7
0
0
0
7
% K
% Leu:
7
63
0
0
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
69
7
0
13
0
7
7
0
7
13
0
0
7
75
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
0
0
69
0
0
0
0
0
7
% Q
% Arg:
0
7
0
0
0
0
0
0
7
0
7
0
0
7
69
% R
% Ser:
7
0
7
75
0
7
0
7
0
7
0
82
0
0
7
% S
% Thr:
0
7
0
7
0
0
0
69
0
0
0
0
0
0
0
% T
% Val:
7
7
0
0
0
0
0
0
13
0
7
7
75
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _